Tribulus terrestris, Fr. – BAI JI LI

Tribulus terrestris, Fr. – BAI JI LI

Dosis: 10-50g/Tag

Das Wirkprofil von Tribulus ähnelt demjenigen vieler wie man in der westlichen Phytotherapie sagen würde „blutreinigender“ Kräuter. Traditionell chinesisch ist die „entschleimende“ Wirkung gemeint.
Diese Mittel stimulieren die Zellen dazu, vermehrt toxische Stoffwechselendprodukte abzubauen und helfen so, durch diese hervorgerufene Schäden zu heilen.
So wirkt Lindera gut beim Metabolischen Syndrom, Krebs, Arteriosklerose und allgemein zur Verlangsamung des Alterungsprozesses, da dieser durch fortschreitende Ablagerung von Oxydationsstoffen mitbedingt und bescheunigt wird.
Die Besonderheit bei Tribulus besteht in seiner Wirkung auf die Reproduktionsorgane. Durch eine zentralnervös bedingte Anregung der Testosteronbildung kommt es insbesondere zur Vermehrung und Kräftigung der Muskulatur.

Weiterhin regt Tribulus die Melaninproduktion in den Haaren und die Dopaminproduktion im Gehirn an.

1. Libidomangel – Impotenz – Oligozoospermia

– Effect of Tribulus terrestris on nicotinamide adenine dinucleotide phosphate-diaphorase activity and androgen receptors in rat brain.

Administration of Tribulus terrestris extract (TT) increased sexual behaviour and intracavernous pressure both in normal and castrated rats and these effects were probably due to the androgen increasing property of TT.

– The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction–an evaluation using primates, rabbit and rat.

In primates, the increases in T (52%), DHT (31%) and DHEAS (29%) at 7.5mg/kg were statistically significant. In rabbits, both T and DHT were increased compared to control, however, only the increases in DHT (by 30% and 32% at 5 and 10mg/kg) were statistically significant. In castrated rats, increases in T levels by 51% and 25% were observed with T and TT extract respectively that were statistically significant.

– Clinical study of Tribulus terrestris Linn. in Oligozoospermia: A double blind study.

The Gokshura granules have shown superior results in the management of Kshina Shukra, as compared to the placebo granules.

– Effects and Mechanism of Action of a Tribulus terrestris Extract on Penile Erection

The T. terrestris extract induced concentration-dependent relaxation of the CC in an organ bath. The mechanism included a reaction involving the nitric oxide/nitric oxide synthase pathway and endothelium of the CC. Moreover, in an in vivo study, the T. terrestris extract showed a significant concentration-dependent increase in ICP. Accordingly, the T. terrestris extract may improve erectile function.

2. Arteriosklerose

– Influence of Tribulus terrestris extract on lipid profile and endothelial structure in developing atherosclerotic lesions in the aorta of rabbits on a high-cholesterol diet.

The ruptured endothelial linings and damaged cellular surfaces increased in EG-I compared to EG-II. Our data indicate that dietary intake of TT can significantly lower serum lipid profiles, decrease endothelial cellular surface damage and rupture and may partially repair the endothelial dysfunction resulting from hyperlipidemia.

– Cellular and Molecular Mechanisms in Vascular Smooth Muscle Cells by which Total Saponin Extracted from Tribulus Terrestris Protects Against Artherosclerosis

These findings provide a new insight into the antiatherosclerotic properties of TSETT and provide a pharmacological basis for the clinical application of TSETT in anti-atherosclerosis.

3. Metabolisches Syndrom

3.1.      Hyperlipidämie

– Influence of Tribulus terrestris extract on lipid profile and endothelial structure in developing atherosclerotic lesions in the aorta of rabbits on a high-cholesterol diet.

The ruptured endothelial linings and damaged cellular surfaces increased in EG-I compared to EG-II. Our data indicate that dietary intake of TT can significantly lower serum lipid profiles, decrease endothelial cellular surface damage and rupture and may partially repair the endothelial dysfunction resulting from hyperlipidemia.

3.2.      Diabetes

– Hypoglycemic and hypolipidemic effects of alcoholic extract of Tribulus alatus in streptozotocin-induced diabetic rats: a comparative study with T. terrestris (Caltrop).

The extracts of both T. alatus and T. terrestris significantly decrease fasting glucose level in diabetic rats.

– The protective effect of Tribulus terrestris in diabetes.

This investigation suggests that the protective effect of TT for STZ-induced diabetic rats may be mediated by inhibiting oxidative stress.

3.3. Hypertonie

– Antihypertensive and vasodilator effects of methanolic and aqueous extracts of Tribulus terrestris in rats.

It was concluded that methanolic and aqueous extracts of Tribulus terrestris possess significant antihypertensive activity in spontaneously hypertensive rats. The antihypertensive effects appeared to result from a direct arterial smooth muscle relaxation possibly involving nitric oxide release and membrane hyperpolarization.

4. Graue Haare

– Effect of Tribulus terrestris extract on melanocyte-stimulating hormone expression in mouse hair follicles

The aqueous extract of Tribulus terrestris can significantly increase MSH expression in the hair follicle melanocytes by activating tyrosinase activity and promoting melanocyte proliferation, melanine synthesis, and epidermal migration of dormant melanocytes.

5. Depressionen

– Effect of tribulus terrestris saponins on behavior and neuroendocrine in chronic mild stress depression rats

To observe the effect of tribulus terrestris saponins (TTS) on behavior and neuroendocrine of chronic mild stress (CMS) depression rats. CMS can affect rat behavior and neuroendocrine and cause depression. TTS has the antagonism on CMS and produce antidepressive effects.

6. Hyperhomocysteinemia

– Comparative antiadhesive properties of crude extract and phenolic fraction isolated from aerial parts of Tribulus pterocarpus during severe hyperhomocysteinemia.

We observed that the phenolic fraction and the crude extract from T. pterocarpus have the inhibitory effect on platelet adhesion during severe hyperhomocysteinemia

7. Krebs
   

7.1.      Hautkrebs

– Saponins from Tribulus terrestris L. protect human keratinocytes from UVB-induced damage

Collectively, our study shows experimental evidence that TT has a preventive efficacy against UVB-induced carcinogenesis and the molecular knowledge on the mechanisms through which TT saponins regulate cell death suggests great potential for TT to be developed into a new medicine for cancer patients

7.2.      Leberkrebs

– Aqueous extract of Tribulus terrestris Linn induces cell growth arrest and apoptosis by down-regulating NF-κB signaling in liver cancer cells

These data showed that TT extract blocks proliferation and induces apoptosis in human liver cancer cells through the inhibition of NF-κB signaling. Aqueous TT extract can be used as an anticancer drug for hepatocellular carcinoma patients

8. Eierstockszysten

– Alternative treatment of ovarian cysts with Tribulus terrestris extract: a rat model

It can be concluded that T. terrestris have a luteinizing effect on ovarian cysts, which may relate to its gonadotropin-like activity; also, a high dose of the extract can efficiently remove ovarian cysts and resume ovarian activity.

TCM

Ein Vergleich des Wirkspektrums von Fr. Tribuli, wie er sich durch die Analyse wissenschaftlicher Studien ergibt, und Benskys TCM-Pharmakopoe ergibt Unterschiede:
Tribulus erscheint laut TCM-Quellen allein als Mittel bei schmerzhaften Verspannungen und Konjunktivitis.
Die Wirkung auf innere Krankheiten wie dem metabolischen Syndrom, Krebs oder Arteriosklerose bleibt aussen vor. Vor allem weiss die TCM-Pharmakopoe nichts über die Hauptwirkung des Mittels auf die Dopamin- Testosteron- und Muskelbildung.
Die 5-Elementeanalyse bildet die Energiedynamik von Fr. Tribuli wie folgt ab:
Blau bedeutet :  TCM-Quellen
Grün bedeutet:  TCM-Quellen und Studien
Schwarz :            Studien
Rot:                      Studien Hauptwirkung

Zum Verständnis der Abkürzungen des Schaubildes siehe

Struktur – und Wandlungsmodell der chinesischen Medizin
http://www.chinesischemedizin.com/CMS/index.php/struktur-und-wandlungsmodell.html