Camellia sinensis, Fol. – Tee

Dosis: 3-15 g/Tag

Tee wirkt als Anregungsmittel bei geistiger und körperlicher Erschöpfung. Es hilft ebenso bei Ablagerungen und Stauungen durch trägen Stoffwechsel. Es besteht zu 50% aus dem Antioxidans Catechin.

1. Fettleber
2. Metabolisches Syndrom
3. Bindegewebsschwäche
4. Neurodegeneration
5. Hypercortisolismus
6. Krebs
7. Sjögren’s syndrom
8. Übergewicht
9. Arthritis
10. Karies

1. Fettleber

Epigallocatechin-3-Gallate (EGCG), a Green Tea Polyphenol, Stimulates Hepatic Autophagy and Lipid Clearance.

In mice fed with high-fat/western style diet (HFW; 60% energy as fat, reduced levels of calcium, vitamin D3, choline, folate, and fiber), EGCG treatment reduces hepatosteatosis and concomitantly increases autophagy

2. Metabolisches Syndrom

2.1.      Hypercholesterinämie

The role of green tea extract and powder in mitigating metabolic syndromes with special reference to hyperglycemia and hypercholesterolemia.

The current research work enables us to conclude that green tea is effective against hypercholesterolemia and hyperglycemia.

2.2.      Diabetes

– The role of green tea extract and powder in mitigating metabolic syndromes with special reference to hyperglycemia and hypercholesterolemia.

The current research work enables us to conclude that green tea is effective against hypercholesterolemia and hyperglycemia.

– Effects of the green tea polyphenol epigallocatechin-3-gallate on high-fat diet-induced insulin resistance and endothelial dysfunction.

From these results, we conclude that supplementation of EGCG improves glucose tolerance, insulin sensitivity, and endothelial function. The results suggest that EGCG may have beneficial health effects in glucose metabolism and endothelial function through modulating HFD-induced inflammatory response.

 

3. Bindegewebsschwäche

Elasto-regenerative properties of polyphenols.

Our results indicate that polyphenols bind to monomeric tropoelastin and enhance coacervation, aid in crosslinking of elastin by increasing lysyl oxidase (LOX) synthesis, and by blocking MMP-2 activity. Thus, polyphenol treatments leads to increased mature elastin fibers synthesis without increasing the production of intracellular tropoelastin.

 

4. Neurodegeneration

– Neuroprotective effects of resveratrol and epigallocatechin gallate polyphenols are mediated by the activation of protein kinase C gamma

The MTT/resazurin and spectrin assays indicated that EGCG and resveratrol protected against GF 109203X-induced cell death and cytoskeleton degeneration, with a maximal effect at 1 and 3 μM, respectively

– (-)-Epigallocatechin-3-Gallate Ameliorates Learning and Memory Deficits by Adjusting the Balance of TrkA/p75NTR Signaling in APP/PS1 Transgenic Mice.

In this study, we found that EGCG treatment (2 mg · kg ^-1 · day ^-1) dramatically ameliorated the cognitive impairments, reduced the overexpressions of Aβ(1-40) and amyloid precursor protein (APP), and inhibited the neuronal apoptosis in the APP/PS1 mice.

 

5. Hypercortisolismus

Green Tea and One of Its Constituents, Epigallocatechine-3-gallate, Are Potent Inhibitors of Human 11β-hydroxysteroid Dehydrogenase Type 1

Our study is the first to provide evidence that the health benefits of green tea and its polyphenolic compounds may be attributed to an inhibition of the cortisol producing enzyme 11β-HSD1

 

6. Krebs

Binding interaction between (-)-epigallocatechin gallate causes impaired spreading of cancer cells on fibrinogen.

EGCG inhibited the spreading of mouse metastatic LL2-Lu3 lung cancer cells on the fibrinogen substratum, which suggested an impairment in the interaction between cancer cells and fibrinogen. Since the interaction between cancer cells and fibrinogen plays an important role in metastasis, the present results suggest, at least partially, that EGCG inhibited metastasis in the mouse models reported previously by inhibiting such an interaction.

6.1.      Leberkrebs

Epigallocatechin-3-gallate inhibits cell growth, induces apoptosis and causes S phase arrest in hepatocellular carcinoma by suppressing the AKT pathway.

The results suggest the potential of EGCG as an anticancer agent in the prevention or treatment of HCC.

6.2.      Bronchialkrebs

Epigallocatechin gallate inhibits the growth of human lung cancer by directly targeting the EGFR signaling pathway.

Moreover, long-term EGCG treatment not only inhibited total and membranous EGFR expression, but also markedly attenuated EGFR nuclear localization and expression of the downstream target gene cyclin D1, indicating that EGCG treatment suppressed EGFR transactivation.

6.3.      Prostatakrebs

Enhanced inhibition of prostate cancer xenograft tumor growth by combining quercetin and green tea.

After 6-weeks of intervention tumor growth was inhibited by 3% (0.2% Q), 15% (0.4% Q), 21% (GT), 28% (GT+0.2% Q) and 45% (GT+0.4% Q) compared to control.

6.4.      Hautkrebs

Green tea polyphenol, (-)-epigallocatechin-3-gallate, induces toxicity in human skin cancer cells by targeting β-catenin signaling

The green tea polyphenol, (-)-epigallocatechin-3-gallate (EGCG), has been shown to have anti-carcinogenic effects in several skin tumor models

 

7. Sjögren’s syndrom

Epigallocatechin gallate inhibits oxidative stress-induced DNA damage and apoptosis in MRL-Fas(lpr) mice with autoimmune sialadenitis via upregulation of heme oxygenase-1 and Bcl-2.

Overexpression of HO-1 and Bcl-2 mediated by EGCG blocked this pathogenic cycle, subsequently resulting in the inhibition of ROS-mediated DNA damage and apoptosis, and protected salivary gland tissues from oxidative stress. Clinically, green tea catechin may have therapeutic efficacy for Sjögren’s syndrome.

 

8. Übergewicht

– Novel insights of dietary polyphenols and obesity.

Here, we evaluated the impact of commonly consumed polyphenols, including green tea catechins, especially epigallocatechin gallates, resveratrol and curcumin, on obesity and obesity-related inflammation. Cellular studies demonstrated that these dietary polyphenols reduce viability of adipocytes and proliferation of preadipocytes, suppress adipocyte differentiation and triglyceride accumulation, stimulate lipolysis and fatty acid β-oxidation, and reduce inflammation.

– Epigallocatechin-3-gallate ameliorates both obesity and autoinflammatory arthritis aggravated by obesity by altering the balance among CD4(+) T-cell subsets.

Thus, EGCG has an anti-inflammatory effect by suppressing STAT3 proteins and Th17-cell differentiation. EGCG thus shows promise for treating autoimmune conditions related to STAT3 or Th17 cells, such as metabolic syndrome, inflammatory arthritis, and some neoplastic diseases.

 

9. Arthritis

Epigallocatechin-3-gallate ameliorates both obesity and autoinflammatory arthritis aggravated by obesity by altering the balance among CD4(+) T-cell subsets.

Thus, EGCG has an anti-inflammatory effect by suppressing STAT3 proteins and Th17-cell differentiation. EGCG thus shows promise for treating autoimmune conditions related to STAT3 or Th17 cells, such as metabolic syndrome, inflammatory arthritis, and some neoplastic diseases.

 

10. Karies

Camellia sinensis (Tea): Implications and role in preventing dental decay.

This article outlines the possible role of these compounds coupled with the presence of high fluoride content in tea to exhibit an anticariogenic effect.

 

TCM

Die 5-Elementeanalyse bildet die Energiedynamik von Camellia wie folgt ab:

Blau bedeutet :  TCM-Quellen
Grün bedeutet:  TCM-Quellen und Studien
Schwarz :            Studien
Rot:                       Studien Hauptwirkung

Zum Verständnis der Abkürzungen des Schaubildes siehe

Struktur – und Wandlungsmodell der chinesischen Medizin
http://www.chinesischemedizin.com/CMS/index.php/struktur-und-wandlungsmodell.html